Facial hyperpigmentation: causes and treatment

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Isotretinoin - induced facial hyperpigmentation : idiosyncratic reaction ?

Isotretinoin is notorious for having a myriad of mucocutaneous side effects including cheilitis, xerodermia, facial erythema, pruritis, hair thinning, and brittle nails, among others. Although photosensitivity is considered to be one of the side effects of oral isotretinoin therapy, cutaneous hyperpigmentation has not, to the best of our knowledge, yet been reported as a side effect. This repor...

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Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency.

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CASE FOR DIAGNOSIS Patchy Facial Hyperpigmentation Hiperpigmentación facial parcheada Medical History

Histology of one of the lesions showed an intact epidermis and the deposition of a dark-yellow material between the collagen fibers in the superficial dermis; the accumulations of this material showed a variable morphology. The adnexa were not affected and there was no inflammatory infiltrate. No signs of melanocyte proliferation or increased melanic pigment in the basement membrane were observ...

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ژورنال

عنوان ژورنال: British Journal of Dermatology

سال: 2013

ISSN: 0007-0963

DOI: 10.1111/bjd.12536